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Losing the Weight Loss Meds

By Holly Wyatt and James Hill

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Leading weight loss maintenance researchers Holly Wyatt, MD, and James Hill, PhD, share key strategies for using food, movement, and mindset to replace the medication, along with specific, actionable strategies for sustainable, lasting success in Losing the Weight Loss Meds.

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ISBN: 9781637747803

Publication Date: December 2025

Publication Date: December 2025

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Description

COMING DECEMBER 2025

Innovative weight loss medications are transforming how doctors treat obesity, diabetes, high cholesterol, and moreโ€”but while these drugs can help you lose weight, the hardest part is keeping the weight off when you stop taking them.

Thatโ€™s why, when youโ€™re shifting away from GLP-1 meds, you need a game plan.

Research shows that most people on weight loss drugs like Ozempic, Wegovy, and Zepbound quickly regain their weight when they stop taking medication. Whether you end treatment due to not feeling great, undesirable side effects, loss of insurance coverage, or you just want to keep your weight off without medication, without a plan in place when your bodyโ€™s natural hunger returns, you risk regaining it all.

Leading weight loss maintenance researchers Holly Wyatt, MD, and James Hill, PhD, share key strategies for using food, movement, and mindset to replace the medication and support long-term weight loss maintenance through an adaptable 10-week transition plan.

Chock-full of specific, actionable strategies for sustainable, lasting success,ย Losing the Weight Loss Medsย offers everything you need to:

  • Develop an eating plan that maximizes satiety and minimizes โ€œfood noiseโ€
  • Use movement to restore your metabolism to one that is more flexible and that burns more calories
  • Adjust your mindstate to become more resilient to better overcome obstacles and find joy in the weight loss maintenance process
  • Effectively troubleshoot weight fluctuations before they result in significant regain
  • Create and maintain a life you love

By embracing the journey and having a strategic plan, you can maintain your new healthier weight with easeโ€”so you never have to worry about weight loss again.

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About the Authors

Holly  Wyatt

Dr. Holly Wyattย is a leading authority in weight loss and long-term weight management, with over 25 years of experience helping people not only achieve significant weight loss but also maintain it for life. Best known as the medical doctor on the hit TV showย Extreme Weight Loss, Dr. Wyatt has guided countless individuals through dramatic transformations, using her expertise in metabolism, nutrition, and behavior change. Coauthor of the bestselling bookย State of Slim, she specializes in creating sustainable, science-based strategies that empower people to reset their metabolism, manage their appetite, and develop healthy, lasting habits.

Dr. Wyattโ€™s career is dedicated to helping people maintain their weight loss and improve their overall well-being by focusing on sustainable lifestyle changes rather than quick fixes. Whether through her clinical programs, media appearances, or one-on-one coaching, Dr. Wyattโ€™s practical, personalized approach inspires people to not just reach their weight goals, but to truly transform their health and their lives in the process.

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James  Hill

Dr. James O. Hillย is a world-renowned expert in obesity, nutrition, and weight management, with over 40 years of groundbreaking research and experience in the field. As the cofounder of the National Weight Control Registry, the largest study of individuals who have successfully maintained long-term weight loss, and coauthor ofย State of Slim, Dr. Hill has pioneered the understanding of sustainable weight loss. His work has been instrumental in developing evidence-based strategies that empower people to achieve lasting weight management through balanced nutrition, physical activity, and behavioral changes.

Dr. Hill has published over 700 peer-reviewed articles and is widely recognized for his contributions to public health, including shaping national policies on obesity prevention and management. His expertise has been featured in major media outlets, and his research has influenced health professionals and individuals worldwide. With a passion for translating science into actionable advice, Dr. Hill continues to help people live healthier, more fulfilling lives by providing practical, long-term solutions for weight maintenance and overall well-being.

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Publication Details

Format: Hardcover

ISBN: 9781637747803

Dimensions: 6 x 9 x 1 in.

Weight: 1 lbs.

Publication Date: December 2025

Format: E-book (epub)

Publication Date: December 2025

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